04
Featured Session · 04 of 35
GI Oncology
GI oncology is being reshaped by molecularly stratified care: ctDNA-guided adjuvant decisions in stage II/III colon cancer (DYNAMIC, GALAXY), MSI-high tumors responding to neoadjuvant dostarlimab and pembrolizumab (with watch-and-wait emerging in rectal cancer), and HER2-positive gastric/GEJ disease driven by trastuzumab deruxtecan and zolbetuximab (CLDN18.2). Pancreatic cancer remains the hardest target, but mRNA neoantigen vaccines, KRAS G12C/G12D inhibitors, and FOLFIRINOX intensification offer incremental gains. Sessions also cover Barrett’s surveillance with WATS3D and AI, and cholangiocarcinoma FGFR2/IDH1-targeted therapy.
Topics covered in this session
- ctDNA-guided adjuvant therapy in colon cancer (DYNAMIC, GALAXY)
- Neoadjuvant immunotherapy in MMR-deficient rectal and colon cancer
- HER2 and CLDN18.2 in gastric/GEJ: trastuzumab deruxtecan, zolbetuximab
- Pancreatic cancer: KRAS G12C/G12D inhibitors and mRNA neoantigen vaccines
- Barrett’s esophagus surveillance: WATS3D, AI and EET
- Cholangiocarcinoma: FGFR2 fusions, IDH1 mutations, targeted therapy
- Hereditary GI cancer syndromes and universal MMR screening
Other Sessions
Explore the full GCGD 2027 program
- 01Inflammatory Bowel Disease
- 02Hepatology & Liver Disease
- 03Endoscopy & Interventional GI
- 05Functional GI & Motility
- 06Gut Microbiome
- 07Pediatric Gastroenterology
- 08Nutrition & Celiac Disease
- 09AI in GI
- 10Eosinophilic Esophagitis
- 11Gastric & Esophageal Cancer
- 12Pancreatic Disease
- 13Biliary & Liver Surgery
- 14Therapeutic Endoscopy
- 15Bariatric & Metabolic Endoscopy
- 16Fatty Liver Disease (MASH)
- 17Viral Hepatitis
- 18GI Bleeding
- 19Diverticular Disease
- 20Colon Polyps & Screening
- 21Helicobacter pylori
- 22GERD & Reflux Disease
- 23Achalasia & Motility
- 24Anorectal Disorders
- 25Small Bowel Disease
- 26Mesenteric Disease
- 27IBS & Functional Pain
- 28Cystic Fibrosis & GI
- 29Geriatric GI
- 30Women's GI Health
- 31Tropical GI Disease
- 32Liver Transplantation
- 33GI Imaging
- 34Capsule Endoscopy
- 35Health Equity in GI